At the time of his birth, his father was the Minister Plenipotentiary of Peru to the United States, a post he retained until his death in 1877.

[1][2] He received his early education in the United States and England, then he studied civil engineering at the Universities of San Marcos, Pisa and Lausanne.

The following year, de Freyre was moved to Bogota, where he successively served as attaché, Second Secretary and Chargé d'affaires.

In 1907 he was appointed First Secretary of the legation in Washington, D.C., then Chargé d'affaires in 1916 and finally promoted to Minister Plenipotentiary in 1917.

In 1924, when de Freyre was serving as Minister in Buenos Aires, he was appointed as Peruvian delegate to the Plebiscitary Commission of Tacna and Arica,[3] by which American Government issued an award arranging the boundary dispute between Peru and Chile produced as a consequence of the War of the Pacific.