María Antonia Santos Plata (10 April 1782–28 June 1819) was a Neogranadine peasant, rebel leader, and heroine.

[1][4] In the late 1810s, she helped galvanize, organize, finance, and lead pro-Bolívar rebel guerrillas from the Province of El Socorro against invading royalist Spanish troops during the Reconquista of the New Granada.

[1] Additionally, Santos Plata and her compatriots allegedly carried out espionage, and smaller-scale guerilla actions.

[9][10] In 1819, she was captured and arrested at her home, the hacienda El Hatillo, alongside her younger brother and her niece.

[8] She was subjected to a show trial, and found guilty of lese-majesty and high treason.