She worked as a postdoctoral scholar at the Cold Spring Harbor Laboratory and at the University of Michigan.

[2] At the Cold Spring Harbor Laboratory, she characterised the apoptotic factors as melanoma suppressors.

[3] After deciding to expand beyond cellular/animal models, Soengas moved to the dermatology department in Michigan, home to the Multidisciplinary Melanoma Clinics.

[2][4] Soengas looks to identify new biomarkers of disease, and the mechanisms of cellular stress that are deregulated in melanoma.

Her group was the first to describe a lymphoreporter (MetAlert) mice for non-invasive imaging of pre-metastatic niches in melanoma.