It is hypothesized that marbled crayfish originated from an error in meiosis resulting in a diploid gamete, which was then fertilized and created a viable triploid individual in a single generation.

[13] Because marbled crayfish are genetically identical, easy to care for,[14] and reproduce at high rates, they are a potential model organism, particularly for studying development.

[12] Marbled crayfish have caused concern as a potential invasive species[4] because only a single individual is needed to establish a new population, and they can reproduce at high rates.

[17] Marbled crayfish inhabit freshwater environments, and have not successfully invaded ecosystems with higher salinity levels due to their reduced ability to reproduce and grow.

The European Union instituted "a total ban on the possession, trade, transport, production and release of these species [including the marbled crayfish] in the wild" in 2016.

[53] Marbled crayfish are prohibited in the American states of Idaho,[54] Missouri,[55] Tennessee,[56][57] Michigan,[58][59] Maryland,[60] and in the Canadian provinces of Saskatchewan[61] and Ontario.

[63] Protein isolates from whole-body homogenate (including chitinous exoskeleton) of Procambarus virginalis are hypothesized to be dense in branched-chain amino acids (BCAA) and leucine (Leu).