He was the music director of the Orchestre national des Pays de la Loire from 1976 to 1994, and from 1995 to 2003 GMD of the Beethoven Orchester Bonn which plays in both opera and concert.

He has worked at major opera houses in Europe and made several recordings, such as Leonore, Beethoven's first version of Fidelio, the piano concertos and symphonies by Camille Saint-Saëns, Honegger's Jeanne d'Arc au bûcher, and Penderecki's St Luke Passion.

"[5] He conducted in 2017 at the Oper Frankfurt a double bill of Debussy's cantata La Damoiselle élue and Honegger's dramatic oratorio Jeanne d'Arc au bûcher, again staged by Ollé, and co-produced with the Teatro Real Madrid.

[6] A reviewer noted that the conductor "creates a unique musical wonderworld" ("Soustrot erschafft eine einzigartige musikalische Wunderwelt"),[7] with pianos, celesta and Ondes Martenots highlighting special moments.

(Prudently and precise in style, the guest conductor Marc Soustrot and the opera orchestra differentiated between the carefully toned Debussy sonority and an interpretation of the broader brush of the Honegger texture, including even crude effects souvereignly).