Vasari claimed that Marcantonio quickly demonstrated more aptitude than Francia, and started designing and producing fashionable waist-buckles (among other items) in niello (engraved metal which is filled in with alloy in a contrasting colour).
[7] From 1505–11, Marcantonio engraved about 80 pieces, with a wide variety of subject matter, from pagan mythology, to religious scenes.
His early copies included Dürer's famous AD monogram, and Dürer made a complaint to the Venetian Government, which won him some legal protection for his monogram, but not his compositions, in Venetian territory - an important case in the slowly evolving history of intellectual property law.
This influence began showing up in engravings titled The Climbers (in which he reproduced part of Michelangelo's Soldiers surprised bathing, also called Battle of Cascina).
Another famous engraving, the Judgement of Paris, dated 1515 or 1516, after Raphael, became the composition source[citation needed] for Édouard Manet when he painted The Luncheon on the Grass.
started a successful printing establishment under a colorgrinder, Il Baveria, that quickly expanded into an engraving school with Marcantonio at the head.
Around 1524, Marcantonio was briefly imprisoned by Pope Clement VII for making the I modi set of erotic engravings, from the designs of Giulio Romano, which were later accompanied by sonnets written by Pietro Aretino.