She attended California State University, Stanislaus and San Francisco State University for three years, intending to become an elementary school teacher, before moving to Los Angeles to pursue a career in comedy.

[1] Her parents immigrated to the United States from El Salvador during the Salvadoran Civil War.

Arguello has opened for Hannibal Buress, Ron Funches, David Alan Grier, Norm Macdonald, Jessimae Peluso, J.

[2] In 2015, Arguello made her national television debut, appearing on Last Call with Carson Daly.

[1] Since then she has appeared several times on the competitive improvisational comedy show @midnight, "winning the Internet" in March 2016 and again in Jan 2017.