He trained at the Mouratoglou Tennis Academy in Paris on an Olympic Solidarity Youth Development Programme Scholarship since the age of 14 and learned to speak French.

Baghdatis kept playing Challengers and qualifying for upper-tier ATP events for the rest of 2005 and found good form towards the end of the year.

[citation needed] Baghdatis entered the Australian Open as an unseeded player, under the coaching of Guillaume Peyre, and produced an unexpected four-set victory over second-seed and world No.

At the Open 13 tournament in Marseille, France, Baghdatis advanced to his second consecutive singles final and the fifth of his career, where he lost to Gilles Simon in two sets.

At the first grass-court tournament of the season in Halle, Baghdatis reached his sixth career singles final by defeating Philipp Kohlschreiber in the semifinals.

At the Delray Beach International Championships, Baghdatis defeated Ernests Gulbis and Dudi Sela before losing to Jérémy Chardy in the quarterfinals in two tiebreaks.

He won his second ATP Challenger Tour title of the season, after defeating Xavier Malisse again, in the final of the Trophée des Alpilles in St. Remy.

He won his opening match in the ATP 250 tournament in Kuala Lumpur, against Lu Yen-hsun, but was beaten by Mikhail Youzhny in straight sets in the next round.

At the Miami Open he beat Juan Ignacio Chela and in the third round, he lost to seventh seed Marin Čilić in straight sets.

He then made a quarterfinal appearance at the Open de Nice Côte d'Azur as the fifth seed, where he was upset by Argentinian Leonardo Mayer in three sets, despite saving 21 of 24 break points in the match.

He went out in the first rounds in all three grass court tournaments he entered by Philipp Petzschner in Halle, Peter Luczak in s-Hertogenbosch, and Lukáš Lacko at Wimbledon.

Appearing as the top seeded player, he beat Igor Andreev for the first time and then came back from a set down to defeat Juan Ignacio Chela to reach the quarterfinals.

Baghdatis started the 2011 season by competing in the Brisbane International, losing in the quarterfinal to defending champion and second-seeded American Andy Roddick in two sets.

Baghdatis had a very quiet summer on the ATP tour, his most noticeable appearance was at the Wimbledon Championships where he was the 32nd seed and gave eventual winner Novak Djokovic a tough test in the third round, losing in four sets, during a point in the match Djokovic was unable to keep his cool on the Centre Court and at the end of losing a long rally repeatedly hit the grass court with his racket.

In the interrupted first-round match on 29–30 August, against Go Soeda of Japan, he won in three sets before scoring an impressive straight-sets victory over Richard Gasquet in the second round.

Baghdatis finished in the Top 100 for the tenth straight year with best results coming at Challenger level (22–2 record), winning four titles: Nottingham (d. Matosevic) in June, back-to-back in Vancouver (d. Dustov) and Aptos (d. Kukushkin) in August and Geneva (d. Przysiezny) in November.

At the Dubai Tennis Championships, Baghdatis defeated for the second time this season David Goffin, before being forced to retire hurt in a final set tie-breaker against Borna Ćorić in the second round.

[25] Baghdatis's grass-court campaign began in Stuttgart, where despite losing, he showed encouraging signs in his three set loss to superstar Rafael Nadal.

In the final, Baghdatis obtained a right groin injury early in the match, severely hampering his performance in his loss to John Isner.

[30] Baghdatis, due to the birth of his second daughter, began his 2016 campaign only a few days before the Australian Open at the exhibition Kooyong Classic where he had competitive matches with Pablo Carreño and Paul-Henri Mathieu.

[37] Baghdatis, however, struggled once again for majority of the clay-court season, recording first-round losses in Bucharest and Madrid, while pulling out of a number of other tournaments.

At the 2017 Chengdu Open, Baghdatis made his last ATP final where he lost against Denis Istomin after being forced to retire in the first set due to a back injury.

At the 2018 Indian Wells Masters, Baghdatis went on a run to the fourth round as a qualifier defeating Yoshihito Nishioka, 14th seed Diego Schwartzman, and Dudi Sela along the way.

At the 2019 Open Sud de France, Baghdatis qualified for the main draw and defeated top seed and defending champion Lucas Pouille in the second round to make the quarterfinals.

He received a wild-card entry into the main draw[41] and defeated Brayden Schnur in the first round in straight sets which would be his last win of his career.

Upon making his debut Cyprus were competing in the lowest division of Davis Cup competition possible and fell one win shy of being promoted in 2000.

He has the longest winning streak in Davis Cup matches of all time with 36 consecutive singles victories, surpassing (in 2016) the previously held record of 33 by Björn Borg.

[46] Two days before his third-round match against Lleyton Hewitt at the 2008 Australian Open, a video posted on YouTube almost a year earlier made headlines in the local media.

In it, Baghdatis is seen holding a flare chanting, among other things, pro-Cyprus slogans such as "Turks out of Cyprus" twice, with the Hellas Fan Club, a group which was later at the centre of a clash with police.

[50] In a statement issued through his manager, Baghdatis said he was "supporting the interest of my country Cyprus, while protesting against a situation that is not recognized by the United Nations".