Libo came from a Roman family that had settled in Hispania generations before, and had returned to Rome more recently.
Libo had a sister, Annia Fundania Faustina, wife of Titus Pomponius Proculus Vitrasius Pollio, whose second consulship was in 176.
To support his co-emperor Lucius Verus' campaign against the Parthians, Marcus Aurelius appointed Libo governor of the province of Syria.
"As Libo had been consul only the previous year, 161," writes Birley, "he must have been in his early thirties, and as a patrician must have lacked military experience."
"[2] As governor, Libo quarreled with the emperor Lucius, taking the attitude that he would only follow the instructions that Marcus gave him.