[1] After her graduation, Fritsch completed three years of internship at the firms of Houghtaling and Dougan, Van Etten & Co. and Morris H.
The same year, she was elected secretary of Oregon's State Board of Architectural Examiners—becoming the first female to hold the position—and held the role until 1956.
Frederick had been diagnosed shortly after their marriage with an incurable disease, and committed suicide in 1934; Margaret adopted an 11-year-old daughter in 1935 to lessen her loneliness.
[1][2] Fritsch was elected to the American Institute of Architects in 1935 and continued working for her firm until 1940, mainly designing residential houses.
After the beginning of World War II, she gave up architecture due to the lack of work and took on a job at the Portland Housing Authority.