Caca-Nikolovska graduated from the St. Kiril i Metodije Law Faculty of the University of Skopje; she passed the bar exam in 1977 and then served as law clerk in the Skopje Regional Court.

[2] In 1994 Caca-Nikolovska served as president of the Commission for parliamentary elections.

[2] In 1997–1998 Caca-Nikolovska served as judge at the Supreme Court of the Republic of Macedonia, then until 2018 as judge from the Republic of Macedonia to the European Court of Human Rights.

[1] She served in multiple professional organisations and human rights organisations, including the Macedonian Judges Association (1994–1998), which she represented at the European and International Association of Judges (1995–2006); the Civil Association Institute for Human Rights in the Republic of Macedonia; the Macedonian Open Society Foundations (2010–2014) and the Helsinki Committee for Human Rights of Macedonia (since 2011).

She has been a lecturer at multiple trainings and conferences on European human rights law and has published several scientific articles on human rights and fundamental freedoms.