She was born circa 1526, in Belchamp St Paul, the third child and the first daughter to Sir John Golding and his first wife, Elizabeth Tonge/Hammond, the daughter of Thomas Tonge and the widow of Reginald Hammond.
Her mother died on 27 November 1527, and her father remarried Ursula Marston (d. 1564), the daughter of William Marston of Horton, Epsom, Surrey, leading to seven younger half-siblings.
Among these was Arthur Golding, a translator of the late Renaissance of otherwise Latin-only Classical texts.
[1] On 1 August 1548, in Belchamp St Paul, Margery married John de Vere, 16th Earl of Oxford.
Shortly after the 16th Earl of Oxford's death in 1562, the Countess of Oxford married Sir Charles Tyrrel (d. 1570), the 6th son of Sir Thomas Tyrell (sic) of Heron, Essex and Constance, daughter of John Blount, Lord Mountjoy.