Margherita Pignatelli Aragona Cortés, duchess d'Andria (1740–1810) was an Italian courtier.
She was born to Prince Fabrizio di Noia and Costanza de' Medici, and married Duke Riccardo Carafa d'Andria in 1767.
She served as principal lady-in-waiting (Mistress of the Robes) to Queen Maria Carolina of Austria.
When the Parthenopean Republic was declared in 1799, however, she became one of its profiled supporters, and became known for her efforts to help the wounded.
She managed to avoid a death sentence for her support of the Republic.