Her most significant work was created under the tutelage of famed American Regionalist painter Thomas Hart Benton.

Margot Peet was born in Kansas City, Missouri in 1903, and grew up in a prosperous merchant family that encouraged her interest in art.

[1] After graduation she attended Emma B. Hopkins French finishing school in New York City, where she received her first formal art training.

[4] Her maternal aunt, Ruth Harris Bohan, was an accomplished oil painter who became an early role model.

In the fall of 1935, when she was married with two small children at home, Peet enrolled in painting classes taught by the famous Regionalist painter, Thomas Hart Benton at the Art Institute, where she also studied with Randall Davey and Ernest Lawson.

Benton selected a still life painting by Peet for an exhibition of his students' work that was held at the Associated American Artists Gallery in New York City.

In 1993, some of Peet's paintings were featured in the exhibit, Under the Influence: The Students of Thomas Hart Benton, at The Albrecht-Kemper Museum of Art in St. Joseph, Missouri.

Peet was involved with multiple organizations in the Kansas City area, including the Westport Garden Club, an investment club, The Beautification Committee for Mission Hills, the Jewel Ball, Kansas City Art Institute, The Nelson-Atkins Museum of Art and Planned Parenthood.