Both her master's thesis and doctoral dissertation were supervised by Urmas Sutrop at the University of Tartu.

She defended her dissertation, Basic Colour Terms in Finno-Ugric and Slavonic Languages: Myths and Facts, in 2008 at the Department of General Linguistics.

[2] Uusküla teaches psycholinguistics, anthropological linguistics, semantics, and pragmatics at Tallinn University.

She has taught at several other European universities, in Roskilde, Verona, Milan, and Budapest.

[2][3] She is the head of the Western European Studies program at Tallinn University's Institute of Humanities, where she is an associate professor of linguistics and translation studies.