Additionally, she is founder and president of a not-for-profit organization, Maria Luisa de Moreno International Foundation, which offers a broad range of social assistance services, and pioneer of the Colombian political party, MIRA.

[3][4][5] Commonly known as Sister Maria Luisa, she has received three honorary doctorates and the Medal Order of Democracy Simon Bolivar, awarded by the House of Representatives of Colombia.

With the policies that she implemented after taking leadership, the Church of God Ministry of Jesus Christ International experienced remarkable growth.

Subsequently, she pursued her long distance university studies and graduated in 1993 with a Bachelor in Linguistics and Literature from Universidad de La Sabana.

In November of that same year, and in partnership with the Office of the Mayor of Bogota, she graduated from Pontificia Universidad Javeriana with a degree in community development and social management.

She constantly records and publishes videos of the Christian gatherings she hosts, known as Bible Studies, which take place in the different countries where the Church of God Ministry of Jesus Christ International has locations.

They can also be heard on various podcast platforms.The material is dubbed into several languages including English, Italian, Portuguese, French, German, Japanese, Swedish, Danish, Dutch, Polish, Russian, Albanian, and Vietnamese.

[13] Since the Church of God Ministry of Jesus Christ was founded, Maria Luisa has sung the hymns and choruses that are played in the congregation.

"[14] She married pastor Luis Eduardo Moreno when she was 17 years old and they had the following children: Cesar Eduardo Moreno, worldwide administrator of the Church of God; Alexandra, Colombian Consul of Judicial Cooperation, Nationalization, and Titling in New York City;[15] Perla, who created the medical foundation Mira Tu Salud;[16] and Ivan Dario, who is president of a virtual university.

[17] A decade after widowing, she married Mexican architect Humberto Romero Medina, with whom she lives in Florida, where she became a United States citizen.

[32] In early 2016, she received the European Campus Stellae Award, for submitting the best research project and was named the Protectress of the First Promotion of master's degrees for this Higher Education Center that year.