She originally studied what would now be called "home economics" at a French boarding school in Weesp.

[2] But, as was common for upper-class young ladies at the time, she also received drawing lessons, from Christiaan Andriessen.

[3] In 1844, she had a showing at the Exhibition of Living Masters and, in 1847, became an honorary member of the "Royal Academy of Fine Arts" in Amsterdam.

Seven years later, they built a home known as the "Villa Grada", where they gave drawing and painting lessons.

[2] Although Vos is primarily known for still lifes, she also did portraits, landscapes and cityscapes, including a series of watercolors depicting Oosterbeek.