A member of the Visual Arts faculty at Bennington College, Ghani is the collaborator and partner of Chitra Ganesh and is represented by Ryan Lee Gallery.

[1] Her work has been featured in venues like the Tate Modern and the National Gallery of Art, and she has produced several projects including Index of the Disappeared as well as films like Like Water From a Stone and What We Left Unfinished.

[2] She has presented her exhibits at the Transmediale (2003), in Liverpool (2004), at EMAP Seoul (2005), at the Tate Modern (2007), at the National Gallery of Art (2008), in Beijing (2009), and in Sharjah (2009, 2011).

In 2013, she made Like Water From a Stone, a project Ghani filmed in Stavanger, Norway about the transformation the country underwent with the discovery of oil in 1969.

[3] Other films, like The Trespassers, shown at the Los Angeles Municipal Art Gallery in 2014, seek to examine the problems inherent in translating languages.

[12] Additionally, she commented that Radio Television Afghanistan has an "amazingly rich archive of audiovisual material deserving of wider attention.