Thresia Chiramel Mankidiyan was born in Puthenchira in Irinjalakuda Revenue Division of Thrissur district on 26 April 1876 as the third of five children of Thoma and Thanda and was later baptized on 3 May 1876 at the church of Saint Mary; she was named in honor of Teresa of Ávila.

Her family was once rich though became poor when her grandfather married off seven daughters after selling property for each costly dowry; this led to her brothers and her father taking up drinking.

Mankidiyan later accepted John Menachery's request in 1912 to join the Carmelites at Ollur and was there from 26 November 1912 until she left on 27 January 1913 because she did not feel drawn to them either.

Mankidiyan was admitted to the local hospital though doctors deemed her condition fatal and she was moved by bullock cart back to her convent where on 7 June 1926 she received the final sacraments and the Viaticum.

titled her as a Servant of God and issued the official "nihil obstat" (nothing against) to the cause while the cognitional process opened on 14 May 1983 and concluded its business on 24 September 1983.

Pope John Paul II named the late religious as Venerable on 28 June 1999 after he confirmed that she had lived a life of heroic virtue.

[4] The investigation of the miracle required for beatification was held in the Trissur eparchy from 28 April 1992 to 26 July 1993 and was validated on 22 January 1999 before receiving the approval of the medical board on 16 November 1999.

After 33 days of fasting and prayer by the whole family, invoking the help of Mariam Thresia, his right foot was straightened during sleep on the night of 21 August 1970.

This double healing was declared inexplicable in terms of medical science by as many as nine doctors in India and Italy and thus met the last canonical requirement for her beatification.

The miraculous healing of the child Christopher received approval from the medical board in Rome in March 2018 and theologians later confirmed it in October 2018.