Mariana Duque Mariño (Spanish pronunciation: [maˈɾjana ˈðuke maˈriɲo];[a] born 12 August 1989) is a Colombian former tennis player.

In 2005, she appeared in her first WTA Tour qualifying in Bogotá and also played on the ITF Women's Circuit.

Duque fell 2006 in the qualifying in Bogotá, won three singles and three doubles titles on the ITF Circuit.

At the Junior French Open, in her first appearance at a Grand Slam tournament, she finished runner-up, making history for Colombia as the first tennis player to reach such instance.

At the US Open, Duque Mariño advanced to the second round by coming back to beat Tamarine Tanasugarn, ranked 19th in the world, after having lost the first set 0–6.

She was also present at the WTA Tour event of Bogotá, where in the first round she confronted Jelena Kostanić Tošić, winning in straight sets.

In the second round, she faced Yvonne Meusburger being the fifth seed in the tournament and against which Mariana Duque wins, in straight sets.

[2] On 11 through 16 July, Duque Mariño competed at the Pan American Games where she won a gold medal.

This marked the first time in the history of women's tennis a Colombian woman had won a gold medal.

Duque Mariño kicked off the Asian swing at the Korea Open where she advanced to the second round defeating Kiki Bertens, before losing to No.

At the Wuhan Open, she qualified by defeating Casey Dellacqua and Christina McHale but failed to keep her momentum going when she lost to rising star Anna Karolína Schmiedlová, in straight sets.

At the China Open, Duque Mariño breezed through qualifying by defeating wildcard Xu Yifan and Magda Linette both in straight sets.