Mariana Fernández de Córdoba y Ayala (c. 1394[1] – 1431), also known as Mariana de Ayala Córdoba y Toledo, was the fourth Lady of Casarrubios del Monte in the province of Toledo.

She was the daughter of Diego Fernández de Córdoba y Carrillo, first Lord of Baena, and Inés Ayala y Toledo, third Lady of Casarrubios del Monte.

Mariana married Fadrique Enríquez de Mendoza, Admiral of Castile and Lord of Medina de Rioseco around July 1425.

[2] They had one daughter, Juana Enríquez (1425–1468), who married John II of Aragon.

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