Mariano Antonio Guadalupe Escobedo de la Peña (16 January 1826 – 22 May 1902) was a Mexican Army general and Governor of Nuevo León.

Mariano Escobedo was born in San Pablo de los Labradores (which is today known as Galeana), Nuevo León on 16 January 1826.

In 1854 he defended from the liberal rows the Plan of Ayutla that ended the dictatorship of Antonio López de Santa Anna.

Later, he was promoted to general and organized an Army Corps which fought against the French invading troops, defeating them and capturing emperor Maximilian I in Querétaro (1867).

With the arrival of General Porfirio Díaz to the presidency, he was exiled to the United States, from which he organized an uprising against the dictator.