Mariano Santo

Mariano Santo (1488 in Barletta – 1577 in Rome) was a prominent surgeon of the 16th century.

Eventually he returned to Baletta in 1520 for the death of his father and married Maddalena Braccio shortly after in 1524.

Mariano’s written work includes the Artium et medicine and the very important Libellus Aureus de lapide a vesica per incisionem extrahendo and the De lapide renum.

Additionally, he was the first in Europe to demonstrate a new surgical technique called "sectio mariana", which employs the use of a new tool, the "esploratorium", for the extraction of renal calculi.

He died in Rome in 1577 and is buried in Santa Maria sopra Minerva church.

Mariano Santo
Proem of the Libellus Aureus