Mariano de la Luz Verdugo (1746 – 1822) was a Spanish soldier and later Mayor of the Pueblo of Los Angeles.
Mariano Verdugo was promoted to the rank of corporal and placed in command of the guard at Mission San Luis Obispo in 1773.
In 1782, when Governor Felipe de Neve's expedition headed back to Mexico via the Colorado River, Verdugo led the military escort of the return trip.
In 1784, Spanish governor Pedro Fages granted grazing rights to Rancho Portezuela, near present day Universal City, to Mariano de la Luz Verdugo.
Mariano married Maria Guadalupe Lugo (–1780) at Mission San Carlos Borromeo de Carmelo in 1775.