The family converted from Protestantism to Roman Catholicism, and became followers of the theologian Cornelius Jansen.
Her sister Louise-Magdeleine Horthemels was an active reproductive engraver who married Charles-Nicolas Cochin, graveur du roi.
[2] Her brothers Daniel and Denys continued in the bookselling trade, while Frédéric Horthemels was also an engraver.
Marie-Anne's first marriage was to the pastry-maker Germain Le Coq, who had worked for King Louis XIV of France (1638–1715) and for the Duchess of Burgundy.
[6][a] The British Museum has an engraved portrait of James Francis Edward Stuart, the Old Pretender, after a painting by Alexis Simon Belle, dated 1720.