Marie-Pierre Gramaglia is a member of the Council of Government of Monaco, on which she serves as Counsellor of the Ministry of Equipment, Environment, and Urban Planning since 2011.
She is the second woman in Monaco's history to be appointed to the council, behind Sophie Thevenoux, who served as Counsellor of Finance and Economy from 2009 to 2011.
In 2001 she was named deputy director of the Business Development Agency, and in 2005 she became a technical advisor in the Ministry of Finance and Economy.
Beginning in 2008 she served as the director of electronic communications, and in 2010 she joined a working group designed to facilitate Monaco's economic development.
[3] In 2013 she announced plans for the development of a new neighborhood, the "Éco-Quartier", to be built on reclaimed land along the Monegaasque coast.