Fredriksson is predominantly known internationally as the lead singer for pop duo Roxette, although she first found success in her native country through her solo albums.

In 1987, ... Efter stormen became the first of her four number one albums in Sweden, and was preceded by the title track—her first top ten hit.

Den ständiga resan was released in 1992 and remains her most successful and critically acclaimed solo album.

[2] MRI scans later indicated she had a malignant brain tumour in the back of her head,[3][4] after which she endured several months of chemotherapy and radiation treatment.

Roxette reconvened in 2009 for "The Neverending World Tour", and the duo subsequently released several studio albums.

[6] An album by Fredriksson's husband Mikael Bolyos, featuring her vocals on three tracks ("In the Corner of Your Eye", "Tell It to My Heart" and "Hometown").