She was the wife of Bertrand IV de La Tour, and the mother of Bertrand V de La Tour who succeeded her as Count of Auvergne and Boulogne.
Her mother died shortly after Marie's birth on 19 September 1376.
[citation needed] Her father died in 1385, when Marie was nine years of age.
She succeeded her cousin Joan II as Countess of Auvergne and Boulogne upon the latter's death in 1424, as Joan's marriages to John, Duke of Berry, and Georges de la Trémoille had been childless.
[citation needed] Her only son, Bertrand succeeded her as count of Auvergne and Boulogne.