Marie Agnes Jakus (born c. 1915) was an American biologist and microscopist specialized in electron microscopic studies of the fine structure of eye tissues.

Jakus received a fellowship from Oberlin College in 1938 to study marine invertebrate zoology at Woods Hole Oceanographic Institution.

She later worked as a graduate assistant at Washington University in St. Louis between 1938 and 1941, during which she received a fellowship in 1941 to return to Woods Hole to study physiology.

[4] In 1951, Jakus joined the Retina Foundation where she developed a national reputation for electron microscopic studies of the fine structure of eye tissues.

ln this capacity, she was responsible for the administration of research grants and programming activities along disease-oriented lines for all disorders of the eye.