[2] The couple had four children: Dora, who served as the Minister of Foreign Affairs of Greece from 2006 to 2009 and Mayor of Athens from 2003 until 2006, Alexandra, a civil-society activist, Katerina (Aikaterini) and Kyriakos, a member of the Hellenic Parliament from the New Democracy party who on 8 July 2019 became Prime Minister of Greece.

Mitsotakis served as the Spouse of the Prime Minister from 1990 to 1993 during her husband's tenure as head of government.

In 1990, soon after taking office, Prime Minister Mitsotakis made his first appearance in the Greek parliament.

[2] Dimas quickly resigned during an official trip to the Soviet Union as a result of Marika's criticism.

[2] Political opponents of Konstantinos Mitsotakis accused her of using food to persuade two members of the Communist Party of Greece to join a 1989 coalition government with the conservatives with the purpose of pursuing corruption charges against Andreas Papandreou.