Mario Baldassarri (born 10 September 1946) is an Italian economist and politician.

Born in Macerata, he was the vice-minister of economy and finance in Silvio Berlusconi's second and third governments, from 2001 to 2006.

He graduated in economics in 1969 and specialized at the Massachusetts Institute of Technology in 1977 with Franco Modigliani, Robert Solow and Paul Samuelson as speakers.

In 2001 he ran for the Chamber of Deputies in the Macerata college: supported by the House of Freedoms, he obtained 43.7% of the votes and was defeated by the candidate of the Olive Tree Valerio Calzolaio.

In the Berlusconi II and III governments he held the position of Deputy Minister for the Economy and Finance (2001–2006).