In 1988, Caldato began his long-term professional association with Beastie Boys when he engineered their second album, Paul's Boutique.

With Adam Horovitz, he produced two albums for the hardcore punk band D.F.L.. Caldato also toured extensively worldwide with Beastie Boys during Check Your Head and Ill Communication, and mixed their live sound.

Caldato has also worked with such artists as Money Mark, Jack Johnson, Soulfly, Beck, Björk, Blur, Cibo Matto, The Cult, Day One, Los Lobos, John Lee Hooker, Manu Chao, Molotov, Super Furry Animals, Gruff Rhys, The John Butler Trio, Yoko Ono, and One Day as a Lion.

Caldato, a Portuguese speaker, has collaborated and produced many Brazilian artists, including Planet Hemp, Marcelo D2, Seu Jorge, Nação Zumbi, Bebel Gilberto, Marisa Monte, Vanessa da Mata, Os Paralamas do Sucesso and Mallu Magalhães.

In 2008 he mixed the debut album of the Argentinian group Banda de Turistas titled Magico Corazon Radiofonico.