Mario Gene J. Mendiola was a Filipino politician who was governor of Occidental Mindoro and a representative of the province in the House of Representatives.

Mario Gene Mendiola became involved in politics at a young age.

He joined politics after his father Pedro Mendiola, a former representative of Occidental Mindoro in the Interim Batasang Pambansa from 1978 to 1986 was killed by a gunman while delivering a speech in Sablayan in April 1986.

[1] He was elected as representative of Occidental Mindoro's lone district in the House of Representatives for the 8th Congress which lasted from 1987 to 1992.

[2] Mario Mendiola would get elected as vice governor of Occidental Mindoro in 2010 serving until 2013.