Millini was born on 9 February 1677 in Rome, Italy.

[1][2] He was related to several cardinals including Antonio Casali, Savo Millini and Giovanni Battista Casali del Drago.

[3] He was promoted to the cardinalate at the request of Empress Maria Theresa of Austria.

[1] He is buried at the Santa Maria del Popolo.

[4] This article about an Italian Catholic cardinal is a stub.