Mario Zanini, or simply Zanini (September 10, 1907 in São Paulo – August 16, 1971 in São Paulo), was a Brazilian painter and interior designer.
As a teenager he studied in the Escola de Belas de São Paulo, or "School of Arts of São Paulo".
He was part of the Grupo Santa Helena, that would be a nucleus for the Família Artística Paulista, or "Artistic Family of São Paulo".
What distinguishes him from the average integrants of the Grupo do Santa Helena and the Família Artística Paulista were his deep, intense colors, almost naive.
He and Alfredo Volpi were the great masters of color in the Brazilian painting history.