[1] In 1984 she obtained a cum laude degree in medicine from Erasmus University Rotterdam.
[1][3][2] She was involved with the discovery of vanishing white matter in the 1990s, in 2014 she said that a treatment based on stem cell transplantation is coming closer.
[4] In 2008, she was one of four winners of the Dutch Spinoza Prize and received a 1,5 million euro grant.
[5] Van der Knaap stated to spend the money on developing treatment for white matter disorders.
[7] Van der Knaap became a member of the Royal Netherlands Academy of Arts and Sciences in 2010.