On May 10, 2022, Dr Timothy Harris, having lost the support of the elected majority to function as Prime Minister and facing a historic Motion of No Confidence in the National Parliament, decided to dissolve the Parliament and purported to revoke the appointment of more than 50% of his former Cabinet, including Brantley.

He completed his higher education at the University of the West Indies where he graduated with a Bachelor of Laws, Upper Second Class Honors.

Brantley has been admitted to the bar in St Kitts and Nevis, Anguilla, Grenada, Antigua and Barbuda and Dominica.

Brantley serves as a member of the National Assembly, representing the conservative, Nevis-based Concerned Citizens' Movement.

He was formerly the Deputy Premier of the Nevis Island Administration and held the portfolio of Minister of Tourism, Health, Culture, Youth, Sports, and Community Development in that government.