Mark Flood is represented by Stuart Shave/Modern Art, London and KARMA, New York.
In 2012, Randy Kennedy wrote in the New York Times that Flood was "a founder of the underground 1980s band Culturcide" who "never sold enough work to say goodbye to his day jobs (Texaco office worker, elementary school teacher's assistant, video clerk, museum assistant").
Flood has worked in several media and formats such as painting, installation, artist's books and photo-collage.
[5] In 2021 Flood collaborated with the jewelry company, love for both of us, on a series of pendants in bronze and gold that referenced Greek sculptures.
[6] Flood has had solo exhibitions at KARMA, New York;[6] the Contemporary Arts Museum Houston; Peres Projects, Berlin, Germany;[3] the Contemporary Art Museum of St Louis; Zach Feuer Gallery, New York;[3] Galerie Rüdiger Schöttle, Munich, Germany; Luxembourg & Dayan, London;[3] American Fine Art, New York; Rubell Museum, Miami,[7] among other venues.