He has received two Academy Award nominations, including one for Best Animated Feature of the year for the 2008 critically acclaimed Kung Fu Panda which he directed alongside John Stevenson.

[4] Osborne's other most well-known work to date, the award-winning stop motion animated short More, has been screened at over 150 film festivals worldwide.

Parts of Bachelor Pad can be seen in the unaired second episode of Taterhole, which was a spin-off of The Rudy and Gogo World Famous Cartoon Show in 1997.

[6] In November 2016, it was reported that Osborne had been hired to direct and co-write an animated film adaptation of Jeff Smith's comic books, Bone.

[7] In April 2017, 20th Century Fox Animation and Blue Sky Studios announced they would produce Escape from Hat, an animated film adaptation of Adam Kline's fantasy book of the same title, with Osborne set to direct and co-write the script with Kline, and Jinko Gotoh producing the film along with Osborne.

[11] Osborne, along with singer Chris Martin, wrote the story of Coldplay's Mylo Xyloto concept album and directed the video of "Hurts Like Heaven".