He appeared in many Broadway plays and musicals from 1903 through 1941, notably creating roles in original musicals by Kurt Weil, Vincent Youmans, Rudolf Friml, and Silvio Hein, and starring in original plays by David Belasco, Edgar Selwyn, William Le Baron, Guy Bolton and George Middleton among others.
[2] His grandfather, Mark Smith I, was a Shakespearean actor and comedian who for a part of his career was manager of the 19th century Booth's Theatre on Broadway.
[3] Mark Smith III began his stage career performing in small roles with his father in productions of two musicals by Charles H. Hoyt: A Milk White Flag and A Trip to Chinatown.
[2] He portrayed Autolycus in the 1904 Broadway revival of William Shakespeare's The Winter's Tale at the Booth's Theatre in a cast led by the acrtress Viola Allen as Hermione.
[10] He then toured as Jack Walkham in Edgar Allan Woolf and George Sylvester Viereck's The Vampire,[2] including performances at Broadway's Hackett Theatre and the Grand Opera House in Chicago in 1909.
[12] At the time of his marriage he was starring in the title role of James Forbes's The Traveling Salesman Park Theatre in Boston,[12] a work he toured in[2] opposite the actress Miriam Nesbitt as his character's love interest.
[13] In 1912 Smith returned to Broadway as Harry Lyon in the original production of Helen Kraft and Frank Mandel's farce Our Wives at Wallack's Theatre.
His film credits included Zaza (1915, as Cascart),[21] Putting It Over (1916, Lemuel Z. Hawksberry),[22] Nearly Married (1917, as Tom Robinson),[23] Annexing Bill (1918, as George Frayne),[24] A Damsel in Distress (1919, as Percy Marsh),[25] The Vengeance of Durand (1919, as "Tabby" Livingston),[26] and Something Different (1920, as Richard Bidgley).
[29] In 1924 he portrayed Parkinson in Vincent Youmans, Walter De Leon, and Zelda Sears's musical Lollipop at the Knickerbocker Theatre.
[34] In 1930 Smith starred as The Husband opposite Alice Brady as his wife in Fanny Hatton's Love, Honor and Betray at Eltinge 42nd Street Theatre.