Robert Mark Wightman (born July 4, 1947) is an electrochemist and professor emeritus of chemistry at the University of North Carolina at Chapel Hill.

[1] At the same time as Wightman's innovations, the microelectrode was developed independently by Martin Fleischmann at the University of Southampton.

[4] From 1989 to his retirement in 2017, Wightman was the William R. Kenan Jr. professor of chemistry at the University of North Carolina at Chapel Hill.

He was appointed to the neurobiology curriculum in 1989 and was given an external faculty position at the Neuroscience Center at UNC - Chapel Hill in 2004.

By coupling these electrodes to fast-scan voltammetric methods, the group has been able to monitor sub-second changes in concentrations of the neurotransmitters dopamine, norepinephrine, and serotonin in response to pharmacological and electrical stimuli.