Markus Grompe is a professor of Pediatrics and practicing physician at Oregon Health & Science University.
[3] This mouse strain has been a useful model of Type I tyrosinemia, a human genetic disease caused by inactivating mutations in the Fah gene.
The mice have been used to model diseases such as malaria and to optimize human gene therapy strategies.
[4] [5] [6] [7] [8] His laboratory has made advances in the discovery of drugs for the chemoprevention of cancer in Fanconi Anemia.
[14] In 2016, he cofounded Ambys Medicines, which develops treatments for advanced liver disease through enhancement or regeneration of hepatocyte activity.