She is the founder and owner of Hamburg Kennedy Photographs, HK Art Advisory, and Picture This Publications located in New York City.

Ms Kennedy went on to work for Alanna Heiss, the founder and direct of PS1 (now known as MoMA PS1), specifically helping to organize the landmark show Arte Povera with curator Germano Celant in 1985.

Ms Kennedy's gallery career started as the New York Director of the Naples-based Galerie Lucio Amelio, the legendary Italian art dealer, curator, working with artists such as Cy Twombly, Keith Haring, Joseph Beuys, Andy Warhol among many others.

and the accompanying book, She helped organize Andy Warhol Vesuvius [Museo di Capodimonte 18 luglio-31 ottobre 1985] and oversaw the production of one of Andy's last prints, Vesuvius, working directly with the artist and Studio and acted as translator for the catalog accompanying the show[3] In 1989 Ms Hamburg Kennedy relocated to Los Angeles and became the Director of the Richard Green Gallery during the first influx of New York galleries opening in Los Angeles and the booming contemporary art world .

In 1996 Ms Kennedy founded Picture This Publications, to publish, edit, curate and partner on over 25 photography books (several with accompanying traveling exhibitions) including: The Kiss: Photographic Images (Greystone 1993); The Nude/Nobuyoshi Araki (H20 Company, 1993); Wedding Days (H20 1994); Little Angels (DAP, 1996); Little Devils (DAP 1996); I Do (DAP 1997); Car Culture (Gibbs Smith, 1997); International Festival of Fashion Photography I (H20 Japan, 1999); Fashion Photography II (H20, 2001); Twin Towers: An Elegy (Picture This Pub, 2002), Variety: Photographs by Nan Goldin (Rizzoli 2006); Havana Libre: Photographs by Michael Dweck (Damiani 2012), Nan Goldin Variety (Rizzoli).

[12] While Ms Hamburg Kennedy holds a strong presence in New York City she recently relocated to Los Angeles where she lives with her husband and 2 dogs and cat with a new gallery opening in Palm Springs, 2022.

[7] Ms Kennedy is an ardent lover of animals, and is generous with sharing profit with philanthropic organizations such as ASPCA and national and local shelters and has been a foster mom and rescuer for dogs for over 35 years.

[3] In 2016, Kennedy worked in collaboration with French curator Jérôme Sans to produce Lipstick Flavor: A Contemporary Art Story with Photography (2016,Damiani)[17][18] In the same 2016 she edited and helped publish Jamel Shabazz.

[19] In 2018, Kennedy completed and released her next book, BKLYN, images of Brooklyn though eyes of contemporary photographers and artists (Rizzoll 2018).