The distillery was used as a strongpoint by a force of more than a hundred rebels under the command of Éamonn Ceannt, which also held the nearby South Dublin Union.

[citation needed] In 1939, the story and history of Marrowbone Lane was immortalized in a play of the same name which was written by Robert Collis and produced and directed by Michael Mac Liammoir and Hilton Edwards.

It tells the story of a young girl from Mayo who marries into a tenement family and is appalled at the living conditions she and her baby will have to endure.

[9] They were mostly French Huguenot, Dutch and Flemish immigrants and lived in the areas around The Coombe including Marrowbone Lane.

[12] These houses with their unique architecture at the time were common in Marrowbone Lane and the surrounding area, but many have since vanished or have been demolished.

[13] Marrowbone Lane is notable for what the National Inventory of Architectural Heritage describes as an "elegant early social housing scheme", designed by Dublin Corporation's Housing Architect Herbert George Simms, and built in the late 1930s, with curved corners that respond to the curve of Marrowbone Lane.