In 1923, the Japanese government creates a new unit ("Code Zero") within the army to counter the rising threat of vampires, as well as their artificial blood source.

As the members of Code Zero carry out their mission, they encounter strange vampires, humans, and phenomena that force them to question their own identities and purpose.

A manga adaptation of the reading play by Kemuri Karakara was run in Monthly Comic Garden from January 4, 2020 to July 5, 2021 and was compiled into three volumes.

[8] On February 6, 2020, Yomiuri-TV Enterprise LTD announced their 50th Anniversary project, a new anime television series directed by Kōhei Hatano to be co-produced by Funimation.

[14] A free-to-play smartphone adventure game titled Mars Red: Edge of the Nightmare (Kawataredoki no Uta) was announced on February 20, 2021 and released on May 20, 2021 in Japan and worldwide on July 9, 2021.