Her other films include Blume in Love (1973), The Cheap Detective (1978), Max Dugan Returns (1983), Heartbreak Ridge (1986), Stella (1990) and Drop Dead Fred (1991).

On television, she appeared in the soap opera Love of Life (1971–72) and received a Primetime Emmy Award nomination for her recurring role on the sitcom Frasier (1997–98).

Mason guest starred in Madam Secretary (2015–16) and The Good Wife (2016), and has had recurring roles on the ABC sitcom The Middle from 2010 to 2017 and the Netflix series Grace and Frankie since 2016.

That same year, Mason co-starred opposite James Caan in the 20th Century Fox film Cinderella Liberty, which netted her an Oscar nomination for Best Actress.

[citation needed] In 1981, Mason starred along with Kristy McNichol, James Coco, and Joan Hackett in Only When I Laugh, Simon's film adaptation of his Broadway comedy-drama The Gingerbread Lady; it was another box-office success.

Despite a stellar cast led by Mason, Donald Sutherland, Jason Robards and Matthew Broderick, the film was a slow starter, becoming more popular after premiering on cable TV and VHS.

[2] Her stage credits include Norman Mailer's The Deer Park, Israel Horovitz's The Indian Wants the Bronx, Neil Simon's The Good Doctor and Joseph Papp's 1974 Richard III at the Lincoln Center.

Mason reunited with Goodbye Girl co-star Richard Dreyfuss and writer Neil Simon in Duncan Weldon and Emanuel Azenberg's production of The Prisoner of Second Avenue in 1999, which was performed at the L.A. Theatre Works shortly after a revival in London's West End.

In August 2005 Mason starred as Hecuba at the Chicago Shakespeare Theater and on Broadway in Steel Magnolias, with Delta Burke, Frances Sternhagen, Rebecca Gayheart, Lily Rabe and Christine Ebersole.

She appeared in A Feminine Ending at Playwrights Horizons, and in the Shakespeare Theater Company's performance of All's Well That Ends Well in Washington, D.C.[5] Recently, she starred in Lillian Hellman's Watch on the Rhine at Arena Stage in Washington, DC and off-Broadway in the Irish Repertory Theatre's production of "Little Gem" which earned her an Outer Critics Circle Award for Outstanding Performance by an Actress in a Play.

As a director, Mason has helmed productions of Neil Simon's Chapter Two and Robert Harling's Steel Magnolias at the Bucks County Playhouse; the first female version of An Act of God with Paige Davis at Arizona Theatre Company; Juno Stories for Second Stage in NYC; the world premiere of Tennessee Williams' Talisman Roses with Amanda Plummer for the Tennessee Williams Festival in Provincetown, Mass.

In the late 1990s, Mason sold herbs wholesale to companies both locally and regionally before starting a line of wellness and bath and body products called "Resting in the River".