The panel was commissioned by the chancellor of the Republic of Florence, Carlo Marsuppini, for the Saint Bernard Chapel in the eponymous church at Arezzo.

It was subsequently split into three parts and sold to privates, and was later acquired by Pope Gregory XVI.

The central one, on his podium with steps and framed by a shell-shaped niche, is the scene of the coronation of Mary: she is kneeling at the feet of Christ, who puts the crown on his head.

At the sides are two symmetrical compositions of three musician angels and two standing saints in the foreground.

The latter, who are connected to the monastic orders, are presenting the two donors, Gregorio Marsuppini and his son Carlo, both kneeling.