Her senate district included the northeast section of Detroit and the cities of Hamtramck, Highland Park, Harper Woods, and the five Grosse Pointes.

As a Michigan Senator, Scott authored Senate Bill 384 of 2005 (Public Act 48), which established the third Saturday of every June as Juneteenth National Freedom Day in Michigan, celebrating the end of slavery in the United States, and which designated November 26 of every year as Sojourner Truth Day, in honor of the Underground Railroad and emancipation leader of the 1800s.

She also authored Senate Bill 736 of 2001, which provides for domestic violence training for Friend of the Court employees; Senate Bill 753 of 2003 (Public Act 431), which established the Childhood Lead Poisoning Prevention and Control Commission; and Senate Bill 1198 of 2006 (Public Act 286), which requires all children enrolled in the WIC supplemental food program to be tested for lead poisoning.

In 2000, State Senator Virgil Smith resigned his seat to take a position in the Wayne County Prosecutor's office.

In 2008, at age 72, Scott entered the Democratic primary race for United States House of Representatives against incumbent U.S. Rep. Carolyn Cheeks Kilpatrick.

However, Scott did not live in the 13th Congressional District and came in third behind the favored challenger, former state representative Mary Waters.

The Foundation also has provided scholarships to high school students to participate in the Youth in Government program, has assisted with a national cervical cancer awareness program, and hosts an annual Sojourner Truth Essay Contest for high school students.