[2] She is most famous as a member of the Them There collective with which she wrote and starred in productions including Horrible Histories, Yonderland, and Ghosts.

[4] Howe-Douglas graduated from RADA in 2003,[5][6] in the same year she appeared in the Christmas Special of The Office, replacing Dawn as the receptionist at Wernham-Hogg.

From 24 April 2006 until 11 May 2007, Howe-Douglas played receptionist Donna Parmar in the BBC daytime soap opera Doctors.

For her role as Donna, Howe-Douglas received nominations for Best Comedy Performance and Best Newcomer at the 2007 British Soap Awards.

[11] From 15 April 2019, Howe-Douglas co-wrote, produced and starred in the BBC sitcom Ghosts, which sees her reunited with the Horrible Histories cast.