[citation needed] She began her legal career with two years in private practice as an associate at the law firm of Sonnett Sale and Kuehne.

[citation needed] In 2002, she was elected unopposed to Florida's Eleventh Judicial Circuit Court, which encompasses Miami-Dade County.

[3] Since 2011, she has been a shareholder at the Miami law firm of Stearns Weaver Miller Weissler Alhadeff & Sitterson, where her practice consists of complex commercial and employment litigation.

In July 2017, Barzee Flores announced she would run in the Democratic primary for Florida's 27th congressional district, being vacated by retiring Republican Ileana Ros-Lehtinen.

[10] After several other Democrats joined the field, in May 2018 she switched to run in the neighboring 25th district to challenge incumbent Republican Mario Díaz-Balart.